Women smokers present with MI earlier

Smoking impairs cardiovascular risk profiles in women so much, they present with acute MI on average nine years earlier, say US researchers.

This research suggests that not only are women more susceptible to the effects of smoking than men, those who do smoke eliminate the male gender bias normally observed in acute MI.

Analysis of a registry of 7,197 patients presenting to hospital with ST-segment elevated MI (STEMI) showed that women normally present with a first STEMI in their late 60s, while men present in their late 50s or early 60s.

Analysis of this cohort divided them according to risk factors including diabetes, hypertension, hypercholesterol, family history and smoking.

Having a family history of MI reduced the average age of presentation by seven years in women and nearly six years in men.

But smoking reduced the age of STEMI presentation by nine years in women from 71 to 62. In contrast, male smoker years earlier than non-smokers.

rachel.liddle@haymarket.com

For more details visit the Scientific Sessions 2007 website

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