Results from The Physician's Health Study, involving 14,641 men aged 50 and over, showed that taking either vitamin E or vitamin C supplements daily had little impact on CVD risk.
The researchers found that compared with placebo, the use of vitamins showed no effect on total mortality.
Instead, vitamin E was associated with a 1.74 times higher risk of haemorrhagic stroke.
Lead researcher Dr Michael Gaziano, from the Brigham and Women's Hospital at Harvard Medical School, said: 'Observational data had showed that vitamins could be beneficial, but our trial data does not support the use of vitamin E and C.'
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