Previous studies have shown that chronic inflammation may be linked to the development of prostate cancer.
For this latest study, the researchers from the University of Rochester Medical Centre in New York compared blood serum PSA levels and NSAID consumption in a group of 1,319 men over the age of 40.
Men who used NSAIDs regularly had PSA levels approximately 10 per cent lower than men who did not take them.
But the researchers said that although regular NSAID use reduced PSA levels, it is still unclear what impact this has on reducing the development of prostate cancer.
They conclude that 'given the widespread consumption of NSAIDs and the regular use of PSA, the potential implications of our findings may be substantial and warrant further investigation'.
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