Statins help preserve renal function in CVD

Statin treatment can help preserve kidney function in patients with chronic kidney disease who also have cardiovascular disease (CVD), according to a review.

The meta-analysis of 27 statin studies, involving 39,704 people, supports previous suggestions that statins could benefit renal function.

A re-analysis of data from 21 studies that included estimated glomerular filtration rates (eGFR) showed that the change in eGFR was a statistically significant 1.22ml/min per year slower in people receiving statins than those in control groups.

Further analysis revealed that statin therapy benefited patients with CVD, who had an average change in eGFR 0.93ml/min per year slower than controls.

Statins did not significantly impact the eGFR of patients with diabetes, hypertensive kidney disease or glomerulonephritis.

Additionally, a random-effects model of 20 studies that measured proteinuria or albuminuria showed that reduction of these parameters was greater in people taking statins than those in control groups, by 0.58 units of standard deviation.

J Am Soc Nephrol Online

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Follow Us:

Just published

Subject access requests to GP practices increased by a third under GDPR

Subject access requests to GP practices increased by a third under GDPR

The number of subject access requests (SARs) GP practices receive each month has...

RCGP criticises GP at Hand video showing antibiotics prescribed for sore throat

RCGP criticises GP at Hand video showing antibiotics prescribed for sore throat

A promotional video for Babylon GP at Hand that shows a patient with a sore throat...

Review into overprescribing aims to give GPs power to challenge hospital scrips

Review into overprescribing aims to give GPs power to challenge hospital scrips

A government review of overprescribing in the NHS could see GPs given more power...

Submit your session ideas for the RCGP Annual Conference 2019

Submit your session ideas for the RCGP Annual Conference 2019

GPs can now submit ideas for sessions at the RCGP Annual Conference in Liverpool,...

Scottish GP workforce increases for first time in 10 years, figures show

Scottish GP workforce increases for first time in 10 years, figures show

GP numbers in Scotland have risen slightly for the first time in 10 years despite...

More than 16m GP practice appointments a year lost to DNAs

More than 16m GP practice appointments a year lost to DNAs

More than 16m appointments at GP practices are lost every year because patients fail...