Sorafenib remains standard therapy for advanced hepatocellular carcinoma

Sorafenib should remain standard therapy for patients with advanced hepatocellular carcinoma, following the negative results of the SEARCH clinical trial, researchers believe.

Liver cancer: standard treatment for hepatocellular carcinoma unchanged (photo: SPL)

The SEARCH trial looked at 720 patients who were randomised 1:1 to receive either erlotinib and sorafenib or sorafenib plus placebo.

The primary endpoint of the phase III  randomised, double-blind, placebo-controlled trial was a 33% increase in the overall survival on the combination treatment in comparison to sorafenib/placebo.

Personalised medicines, access to cancer drugs and to palliative care are the main issues faced by oncology patients and their healthcare professionals in Europe and worldwide, according to the organisers of the 2012 meeting of the European Society of Medical Oncology.

According to a study from Oxford University annual healthcare costs per head of population for cancer range from 32 to 165 euros across EU countries.

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in


Just published

BMA Scotland GP committee chair Dr Andrew Buist

General practice in Scotland 'in serious trouble', warns BMA Scotland GP chair

General practice in Scotland has reached a tipping point, with demand far outstripping...

Hospital entrance

NHS England issues warning over norovirus and rising winter pressures

Almost three times as many people were in hospital with norovirus last week compared...

BMA Northern Ireland GP committee chair Dr Alan Stout

Northern Ireland GPs face deepest-ever crisis as practices hand back contracts

Northern Ireland's GP leader has warned that general practice in the region is facing...

GP consulting room

GP appointments hit record high of over 34m in October

GP practices delivered a record 34.3m appointments in October this year excluding...

GP consultation

New contract that enforces continuity would make GPs and patients safer, says watchdog

A new GP contract that makes continuity of care an 'essential requirement' for practices...

GP receptionist on the phone

Some practices to receive funding to upgrade digital phone systems

GP practices whose digital phone systems do not meet new NHS England standards will...