Should we return to the old antidepressants?

Recent research has shaken the confidence of many in the efficacy of SSRIs in depression (GP, 7 March).

The message is loud and clear: clinicians need to move towards cognitive or psychological therapy to deal with depression. But this is time consuming and expensive, and will put a strain on funding.

One wonders about good old tricyclics, which gave good results for decades, apart from their side-effects.

Perhaps we should consider them again.

Dr Hari Nawal, Bedford.

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