The 60-year-old grandmother-of-eight worked at the Central Surgery, Barton Upon Humber, North Lincolnshire, where she met her GP husband Tim.
She started baking on her retirement seven years ago and is described on the show's website as 'full of energy and ideas' and 'known for her sense of humour'.
It adds: 'She and her husband renovated a house in the south of France and her time spent there has influenced her baking. She made friends with a French chef with whom she discusses ideas and learns new techniques, and she pushed herself to improve her French so that she can read original French recipes.'
She told the Hull Daily Mail of her #GBBO experience: ''It is the best thing I’ve ever done in my life. It was refreshing being amongst lots of young people and there was a lot of laughter. It is so tense and difficult, but great fun. Everyone involved is brilliant.'
A message from the Lincolnshire Co-op on the show's website says: 'Good luck Nancy! Everyone at Lincolnshire Co-op are rooting for you, cannot wait to see what you cook up on the show.' Tonight's baking includes Swiss rolls and a showstopper challenge of 36 miniature cakes.
The show starts at 8pm tonight and the final is on 8 October.