Research Brief: Genetic factor in hearing loss

A gene responsible for common hearing loss has been identified for the first time, Belgian researchers told the annual conference of the European Society of Human Genetics in Nice, France.

They looked at a gene called TGBF1 which they already knew had non-genetic involvement in otosclerosis. Single nucleotide polymorphism (SNP) analysis was used to compare 630 patients with otosclerosis with a control group. The findings showed that an amino acid-changing SNP in TGBF1 influenced the susceptibility for otosclerosis.

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