Research brief: ACE-inhibitors help advanced renal failure

Patients with advanced renal failure may benefit from treatment with an ACE inhibitor, Chinese research has found. In a trial of 224 patients with advanced renal failure, treatment with the ACE inhibitor benazepril was found to reduce the risk of severe renal disease, raised serum creatine levels or death by 43 per cent. The effect was independent of any effects on BP. An editorial on the findings suggested that ACE inhibitors should replace treatment with other anti-hypertensives if the results are confirmed by other studies and differences between Chinese and Western populations are shown to be transferrable. (N Engl J Med 2006; 354: 131-40, 189-91).


Have you registered with us yet?

Register now to enjoy more articles and free email bulletins


Already registered?

Sign in

Before commenting please read our rules for commenting on articles.

If you see a comment you find offensive, you can flag it as inappropriate. In the top right-hand corner of an individual comment, you will see 'flag as inappropriate'. Clicking this prompts us to review the comment. For further information see our rules for commenting on articles.

comments powered by Disqus