Dr Gerada had previously been awarded the Woman of Achievement Award for the medicine and healthcare category.
The Women in the City Woman of Achievement Award aims to recognise the outstanding contribution women make to the City and identify those who are actively promoting and encouraging the progress of women above and beyond their everyday job.
Dr Gerada beat six other category winners to win the overall award.
She has won a prize which includes a place on the Accelerated Development Program delivered by the University of Chicago Booth School of Business at its London campus.
Speaking on Twitter, Dr Gerada expressed her delight at having won. She tweeted: ‘Thanks amazing prize - Leadership course with Chicago Booth school of Business. Might teach me (to) run (the) NHS!’