Protein could treat osteoporosis

A dramatic increase in the bone mass of mice after changes to the protein NFATc1 has led to hopes of a new osteoporosis treatment.

The study was prompted after observing a fall in bone mass in patients taking the immunosuppressant drug, cyclosporine, which is known to trigger changes in the NFATc family of proteins (Developmental Cell, 2006 10: 777–82). Pictured is a scanning electron micrograph of a fractured finger bone affected by osteoporosis.

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