Professor Helen Lester, professor of primary care research at the University of Manchester, said piloting meant potential indicators could be axed before being passed to negotiators at the GPC and NHS Employers.
'Of 13 indicators that we were working on piloting, 11 actually got through the advisory committee and went on to be negotiated,' she said.
One of these, for palliative care was dropped due to the potential for patient harm. Professor Lester explained how qualitative feedback from GPs had caused concern.
'A lot of the practices were already asking the question as part of the Gold Standards Framework (GSF),' she said.
'But what they said to us was that, as part of a whole package of questions within the GSF, it worked nicely, but if you take it as an isolated QOF indicator it can cause patient harm.
'This is a complex issue with patients who are incredibly vulnerable and are there not possible unintended consequences of making this a tick box exercise? That is what we heard very clearly.'
Professor Lester said a minority of GPs in the pilot had given examples of what would be considered poor practice.
She said: 'There are some 53,000 people on the palliative care register. If only 10 per cent of practices missed the spirit of the indicator in the way I described, you would have 5,000 incredibly vulnerable people being asked something very inappropriate.'