NICE preliminary guidance recommends the use of endothelin receptor antagonists for the treatment of PAH.
Currently, only supportive care, such as anticoagulants, diuretics and calcium channel blockers, are available for those suffering from PAH.
NICE recommends use of sildenafil and, if the treatment is contraindicated or poorly tolerated, bosentan and sitaxentan could be prescribed.
NICE will conduct a second appraisal meeting next month to consider any feedback from the preliminary recommendations.
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