Optimal dosing times are vital

Adjusting the time at which drugs for conditions such as hypertension are taken can be as effective for some patients as changing treatment regimen, a review suggests.

A team from Zhejiang University, China, examined published studies on the optimal time to take once-daily oral medicines. It found many drugs' efficacy could be improved and adverse events reduced by timing of dosing. Once-daily medicines without specific requirements for dosing time should be taken at the same time every day.

Deciding when to take a medicine may be particularly important for conditions that are not being effectively treated on current therapies, it said.

tom.moberly@haymarket.com

  • Int J Clin Pract 2008; 62: 1,560-71.

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