Non-selective NSAIDs deemed acceptable

The European Medicines Agency (EMEA) has concluded the risk-benefit balance for non-selective NSAIDs remains favourable.

Arthitic hand
Arthitic hand
This conclusion has been drawn from the review announced in September of this year [http://www.healthcarerepublic.com/news/Nurse/LatestNews/595593/emea%20to%20review%20non-selective%20nsaids].

The Committee for Medicinal Products for Human Use (CHMP), and committee within the EMEA, concluded that:
  • Non-selective NSAIDs are important treatments for arthritis and other painful conditions.
  • It cannot be excluded that non-selective NSAIDs may be associated with a small increase in the absolute risk for thrombotic events, especially when used at high doses for long-term treatment.
  • The overall benefit-risk balance for non-selective NSAIDs remains favourable when used in accordance with the product information, namely on the basis of the overall safety profile of the respective non-selective NSAID, and taking into account the patient's individual risk factors (for example gastrointestinal, cardiovascular and renal).

The risk-benefit of piroxicam is being assessed separately.

The CHMP confirmed its previous advice that patients should receive the lowest dose of non-selective NSAID, for the shortest duration possible.

MIMS link

Musculoskeletal pain/inflammation 

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Follow Us:

Just published

BMA GP chair: 'GPs let down by tone deaf NHS demands on face-to-face appointments'

BMA GP chair: 'GPs let down by tone deaf NHS demands on face-to-face appointments'

NHS England has let down general practice with its 'tone deaf' demand for all patients...

GPs told to offer face-to-face appointments for all patients

GPs told to offer face-to-face appointments for all patients

GPs have condemned a 'blanket' demand from NHS England that all patients should be...

GP federation network seeks to boost primary care representation amid NHS reforms

GP federation network seeks to boost primary care representation amid NHS reforms

The NHS Confederation has set up a national network for GP federations in a bid to...

Sharp rise in GPs seeking mental health support during past year

Sharp rise in GPs seeking mental health support during past year

The number of GPs seeking help from NHS Practitioner Health, the specialist service...

Podcast: The GP workload crisis, mental wellbeing and vaccination success

Podcast: The GP workload crisis, mental wellbeing and vaccination success

In this episode of our new podcast Talking General Practice we look at the GP workload...

Long wait for COVID-19 public inquiry 'could drive doctors to quit NHS'

Long wait for COVID-19 public inquiry 'could drive doctors to quit NHS'

Doctors' leaders have criticised government plans to delay a public inquiry into...