Non-dipping BP 'needs aggressive therapy'

Patients whose BP does not fall overnight are at increased risk of adverse outcomes from CVD and should be targeted for more aggressive treatment, results of a new study suggest.

Researchers performed 24-hour BP monitoring on 556 patients with resistant hypertension (RH).

After controlling for other risk factors, patients with a non-dipping BP pattern were at 2.3 times greater risk of cardiovascular mortality.

'The nondipping pattern represents an important risk marker for cardiovascular morbidity and mortality, above and beyond other traditional risk factors,' the researchers said.

'Patients with uncontrolled true RH with reduced or reverted dipping patterns should be considered at very high risk for the future occurrence of fatal or nonfatal cardiovascular events and should be treated more aggressively,' they added.

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