NICE offers advice on fractures drug

NICE issued advice last week on the fracture prevention treatment denosumab, the diabetes drug liraglutide and the cardiovascular treatment clopidogrel.

The institute backed denosumab (Prolia) for some postmenopausal women at increased risk of osteoporotic fractures if other NHS treatments are unsuitable.

NICE has also issued final guidance approving the use of the drug liraglutide for some diabetes patients. PCTs must now fund the drug for eligible patients whose clinicians wish to prescribe it.

The treatment can be given to patients with a BMI over 35 if other treatments have failed, or those with a BMI under 35 if they are not suitable for insulin. The institute has also backed wider use of clopidogrel and dipyridamole for preventing occlusive vascular events.

In guidance now out for consultation, clopidogrel can be offered to patients who have had ischaemic stroke, peripheral arterial disease or multivascular disease. But it is only recommended for MI if aspirin is unsuitable.

Modified-release dipyridamole plus aspirin may be considered for patients who have had a TIA, NICE says.

For stroke patients, this should be recommended only when clopidogrel is not tolerated or contraindicated. It should be offered alone only when treatment with clopidogrel and aspirin are unsuitable in this patient group.

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Follow Us:

Just published

Practices handed one-month opt-out window as revamped network DES unveiled

Practices handed one-month opt-out window as revamped network DES unveiled

NHS England has unveiled a revamped DES package for 2020/21 confirming new targets,...

GPs delivered huge rise in face-to-face consultations in week before NHS England letter

GPs delivered huge rise in face-to-face consultations in week before NHS England letter

GPs delivered a huge increase in face-to-face appointments in the week before NHS...

RCGP facing legal action over stance on assisted dying

RCGP facing legal action over stance on assisted dying

The RCGP is facing legal action over its decision to remain opposed to assisted dying...

Medeconomics Live aims to help practices thrive under the new GP contract

Medeconomics Live aims to help practices thrive under the new GP contract

The one-day, virtual Medeconomics Live conference aims to provide practices with...

GPs face wave of abuse and complaints after NHS England face-to-face appointments claims

GPs face wave of abuse and complaints after NHS England face-to-face appointments claims

GP practices have faced a wave of abuse and complaints after a letter from NHS England...

Government denies plan to make GPs 'gatekeepers' of COVID-19 testing

Government denies plan to make GPs 'gatekeepers' of COVID-19 testing

The government has denied plans to make GPs 'gatekeepers' of the struggling COVID-19...