The guidance recommends that rimonabant be used as an addition to diet and exercise for adults who are obese or overweight and who have had an inadequate response to orlistat and sibutramine.
Treatment with rimonabant should be continued beyond six months only if the patient has lost at least 5 per cent of their initial body weight since using the drug.
But rimonabant treatment should be stopped if the patient returns to their pre-treatment weight, and treatment should not be continued for longer than two years without a formal clinical assessment.
Andrew Dillon, executive lead for the NICE obesity guidelines, said: ‘This is good news for patients for whom orlistat and sibutramine are not effective.’
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