In a letter to senior NHS managers, Mr Nicholson sets out a framework for managing the transition from PCT to GP commissioning.
SHAs will oversee the transition and a series of regional commissioning leads have been appointed to 'bridge the gap' between the incoming and outgoing organisations.
He warned executives: ‘this is not a race to establish the first or the most consortia. The proposals represent a fundamental change...it is certainly not about replicating current structures with some new players involved.'
Mr Nicholson said running costs of the new system must ‘start and remain low’.
Mr Nicholson has also answered a series of frequently asked questions that have arisen since the White Paper was published.