New guidance on alteplase for acute ischaemic stroke

NICE has published guidance on the use of alteplase in the treatment of patients with an acute ischaemic stroke.

It recommends that alteplase should only be used by a specialist in the management of acute stroke. Treatment should be initiated within three hours of onset of the stroke symptoms, and after prior exclusion of intracranial haemorrhage. Alteplase is not indicated for acute ischaemic stroke in children under 18 years or adults over 80 years.

A boxed summary of this guidance can be found in MIMS next to the drug entry for alteplase.

The full guidance is available at

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