New diabetes test criteria will miss a third of cases

Changing diagnosis criteria for type-2 diabetes will lead to substantial changes in the prevalence of the disease in different ethnic groups, research shows.

Research has shown that OGTT is better at detecting diabetes in those of South Asian origin
Research has shown that OGTT is better at detecting diabetes in those of South Asian origin

Dirk Christensen and colleagues from the University of Copenhagen looked at screen-detected diabetes prevalence. They compared the degree of diagnostic agreement between oral glucose tolerance test (OGTT) criteria and HbA1c-diagnostic criteria.

HbA1c-only tests have been proposed by an international expert panel. If the WHO backs this view, the DoH and Diabetes UK will consider it too.

But Dr Christensen and colleagues' results suggest that, in those of South Asian origin, an HbA1c-based test would miss more than a third of cases that OGTT criteria would pick up.

The researchers argue that a shift to an HbA1c-based diagnosis for diabetes will have substantially different consequences for diabetes prevalence across ethnic groups and populations.

Last month, a leading biochemist warned that using HbA1c alone to screen for type-2 diabetes risked misdiagnosing large numbers of patients. In people of African, Mediterranean or south-east Asian heritage with diabetes, HbA1c can be inaccurate, he pointed out.

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Follow Us:

Just published

UK COVID-19 vaccination programme tracker

UK COVID-19 vaccination programme tracker

GPs across the UK are playing a leading role in the largest-ever NHS vaccination...

GP-led sites behind almost three quarters of COVID-19 jabs in England

GP-led sites behind almost three quarters of COVID-19 jabs in England

GP-led vaccination sites have delivered nearly three quarters of COVID-19 vaccine...

GPs should ignore calls to throw away usable COVID-19 vaccine, says RCGP

GPs should ignore calls to throw away usable COVID-19 vaccine, says RCGP

Suggestions that vaccination sites should throw away usable doses of COVID-19 vaccine...

GPs urged to use influence to dispel COVID-19 vaccine myths and boost BAME uptake

GPs urged to use influence to dispel COVID-19 vaccine myths and boost BAME uptake

GPs have been encouraged to use their ‘huge influence’ to bust misinformation around...

Six in 10 over-80s vaccinated against COVID-19 as figures expose regional variation

Six in 10 over-80s vaccinated against COVID-19 as figures expose regional variation

Six in 10 people aged over 80 in England received a first dose of COVID-19 vaccine...

Summary of changes to the GP contract 2021/22

Summary of changes to the GP contract 2021/22

The BMA and NHS England have agreed minor changes to the GP contract for 2021/22....