The lobby group, led by chairman and GP Dr Charles Alessi, will become the Confederation’s primary care provider network. The organisation will be fully integrated by April 2015.
The NHS Confederation represents commissioning and provider organisations.
Dr Alessi said: ‘The NAPC has always championed high quality primary care provision that is tailored to the needs of local communities reaching beyond traditional general practice in pursuit of improvements to the health of the populations we serve.
'The opportunity for greater organisation and innovation within primary care, both at home and abroad, as an integral part of the local care system has never been greater or more pressing. The NHS Confederation provides the right platform for us to act as the exclusive vehicle for primary care provision.
'This will allow us to expand our membership base and increase our influence and effectiveness in all areas of our work.’
NHS Confederation chief operating officer Matt Tee said the merger would further widen the diversity of primary care providers within NAPC and ensure they play a central role shaping future provision.