Metabolic syndrome alters heart function

The metabolic syndrome can cause severe abnormalities in heart structure and function, Portuguese research suggests.

The link depended on the number of features of the metabolic syndrome - characterised by high BP, blood sugar irregularities and excess weight around the waist.

Moreover, the association between the metabolic syndrome and cardiac function is independent of the 10-year predicted risk of CHD using the Framingham score and is not fully explained by a patient's BP, claim the researchers.

The study involved 684 adults over 45, who were randomly selected from the local region.

Participants were interviewed by a doctor and were assessed for ECG, BP and levels of blood glucose and cholesterol. A fifth of participants had the metabolic syndrome and 75 per cent had a BP of 130/80 mmHg or greater.

Cardiac abnormalities affected 8.4 per cent of women and 5.2 per cent of men having symptomatic cardiac dysfunction.

Multivariate regression to assess the link between the number of metabolic syndrome features and cardiac structure and function showed that, after adjustments, the risk of symptomatic cardiac dysfunction was more than quadrupled in those with four to five metabolic syndrome features when compared with those who had none.

Left ventricular (LV) diastolic dysfunction, mean LV mass, LV diameter and left atrium diameter all increased significantly with the number of features of metabolic syndrome after adjustment for systolic BP.

BMC Cardiovascular Disorders 2007  

What do you think? Comment below or email healthcare.republic@haymarket.com

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Follow Us:

Just published

Next-day GP appointments three times as likely to be missed as same-day bookings

Next-day GP appointments three times as likely to be missed as same-day bookings

Patients are nearly three times as likely to miss appointments booked with GP practices...

Outsourcing GP services overseas could be 'legal minefield', experts warn

Outsourcing GP services overseas could be 'legal minefield', experts warn

Using digital technology to outsource GP consultations overseas could leave the NHS...

RCGP sets out advice for GPs on prescribing cannabis

RCGP sets out advice for GPs on prescribing cannabis

GPs should warn patients hoping to access cannabis-based medicines that the process...

Every patient in England has access to extended hours GP appointments

Every patient in England has access to extended hours GP appointments

Every patient in England now has access to extended hours GP appointments, NHS England...

GP at Hand takes down video that sent 'wrong message' about antibiotics

GP at Hand takes down video that sent 'wrong message' about antibiotics

GP at Hand has removed a promotional video from its website that showed a patient...

GP Job of the Week: Salaried GP, Manchester

GP Job of the Week: Salaried GP, Manchester

The Robert Darbishire Practice is a not-for-profit social enterprise looking for...