Kidney function impairment linked to raised risk of stroke

Impaired kidney function raises the risk of stroke by almost half, research shows.

Kidney: eGFR rates studied (Photograph: SPL)
Kidney: eGFR rates studied (Photograph: SPL)

Patients with reduced estimated glomerular filtration rate (eGFR) had a 43 per cent greater risk of stroke than those with normal rates, a Taiwanese meta-analysis showed.

The authors believe the findings may warrant the use of low eGFR as a marker for increased stroke risk.

A team led by Meng Lee of the Chang Gung University College of Medicine, Taiwan, examined 21 studies involving 284,672 patients. In total, 7,863 strokes occurred in this group.

Their study compared recorded eGFR against the numbers of strokes, with a follow-up time of between three and 15 years. A low rate was deemed to be below 60ml/min/1.73m2.

Patients with low eGFR at baseline were much more likely to have had a stroke.

But there was no clear evidence of increased risk among patients with eGFR between 60-90ml/min/1.73m2. The findings also suggested that Asian people with low eGFR may be at even higher risk of stroke.

In a separate study, a team from Cambridge University that found patients with kidney disease had an increased risk of CHD. Among 16,958 participants in the study, 1,210 had CKD at the start of the study.

Those with stage 1 disease had 55 per cent greater risk of CHD than those without CKD. This rose to more than a four-fold risk increase among those with stage 4 disease.

Stephen Robinson

GP Online recommends

BMJ 2010 online

Read more

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Follow Us:

Just published

NHS England pledges £30m for GPs to boost long COVID diagnosis and care

NHS England pledges £30m for GPs to boost long COVID diagnosis and care

NHS England has promised £30m for general practice to improve diagnosis and care...

Second dose COVID jabs for over-40s to be accelerated as lifting restrictions is delayed

Second dose COVID jabs for over-40s to be accelerated as lifting restrictions is delayed

Second doses of COVID-19 vaccines in England will be 'accelerated' for all over-40s...

BMA backs negligence action against GMC and hospital over doctor's suicide

BMA backs negligence action against GMC and hospital over doctor's suicide

The BMA is supporting legal action over alleged negligence and under the Human Rights...

GPs recognised in Queen's birthday honours

GPs recognised in Queen's birthday honours

GPs are among those who have been recognised in the Queen's birthday honours.

UK COVID-19 vaccination programme tracker

UK COVID-19 vaccination programme tracker

GPs across the UK are playing a leading role in the largest-ever NHS vaccination...

The healthcare crisis in Myanmar - how UK GPs can help

The healthcare crisis in Myanmar - how UK GPs can help

Dr Jim Brockbank from Myanmar UK GP Health Action provides an update on how the military...