Kidney cancer therapies may improve quality of life

Kidney cancer drugs in development could improve patients' quality of life and allow more effective treatment, according to Robert Hawkins of Manchester University.

Change to kidney cancer drugs
Change to kidney cancer drugs

Drugs such as sunitinib have represented a 'step change' in kidney cancer treatment in the past few years, but have a number of side-effects, Professor Hawkins said.

These can be significant given that people take sunitinib for a year on average, but can be on the drug indefinitely, he said.

Professor Hawkins told GP newspaper that data on the developmental drug pazopanib suggested it had fewer 'off-target' effects than sunitinib.

'Pazopanib is much more specific which potentially leads to fewer side-effects,' he said.

'There are two likely benefits. One is that it will lead to a better quality of life. Also, patients may tolerate the treatment at a fuller dose for longer.'

He said patients often could not tolerate the maximum dose of sunitinib.

Promising data on regorafenib, another agent targeting the same receptor, were also presented at the conference.

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Follow Us:

Just published

Most GP care should be face-to-face post-COVID, says RCGP

Most GP care should be face-to-face post-COVID, says RCGP

General practice faces a 'rebalancing' between face-to-face and remote consultations...

GP funding formula needs radical overhaul, report warns

GP funding formula needs radical overhaul, report warns

General practice needs more investment and a radical overhaul of its funding formula...

Coronavirus: Key guidance GPs need to know about COVID-19

Coronavirus: Key guidance GPs need to know about COVID-19

GPonline provides an overview of the key guidance relating to coronavirus, including...

Map: Which CCGs have the highest COVID-19 vaccine coverage?

Map: Which CCGs have the highest COVID-19 vaccine coverage?

Tens of millions of COVID-19 jabs have been administered across England, but how...

How to avoid burnout as a doctor

How to avoid burnout as a doctor

Dr Patrice Baptiste recently suffered from burnout, here she offers some practical...

UK COVID-19 vaccination programme tracker

UK COVID-19 vaccination programme tracker

GPs across the UK are playing a leading role in the largest-ever NHS vaccination...