They re-analysed the data from seven studies which looked at the risk of infertility associated with ileal pouch-anal anastomosis (IPAA), a surgical procedure carried out to alleviate the symptoms of severe UC.
Infertility was defined as failing to achieve pregnancy within 12 months of attempting conception.
A total of 892 women from Sweden, the US, Canada and the UK attempted conception either while taking medical treatment for UC, or after undergoing IPAA for the condition.
Women who underwent IPAA had an infertility rate of 48 per cent, compared to 14.6 per cent in those on drug treatment.
Infertility associated with IPAA may be caused by scarring to the fallopian tubes as a result of the procedure.
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