Immune effects of statins studied

Statins could be used to reduce inflammation in the vascular system, research suggests.

A US study found that statins could reduce the pathogenic activity of immune cells.

Immune system T-cells have been shown to cause inflammation in the cardiovascular system. Research has also shown that the Kruppel-like factor 2 (KLF2) protein has an anti-inflammatory effect and cut pathogenic activity of T-cells.

The US team measured the effects of statin treatment on mouse T-cells and found the drug was able to increase the expression of KLF2, leading to reduced myocarditis. They suggest that using statins to target T-cell pathogenesis could help reduce cardiovascular disease.

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