Ibuprofen slows lung decline in CF patients

High-dose ibuprofen can slow the rate of lung decline in children with cystic fibrosis, according to a Cochrane review.

The updated review supports the theory that long-term high-dose treatment with the anti-inflammatory drug can slow down lung tissue deterioration.

The latest review included four trials involving 287 patients aged five to 39 years, who were followed-up for a maximum of four years.

The studies provided some evidence that ibuprofen could slow lung decline. In one study, people treated with ibuprofen before the age of 13 had an annual 1.5 per cent drop in forced expiratory volume in 1 second (FEV1), compared with more than 4 per cent in those given placebo.

However, ibuprofen in cystic fibrosis is not currently recommended for routine use and patients should only be given the therapy in a specialist centre, warn the review authors.

rachel.liddle@haymarket.com

Comment below and tell us what you think

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Follow Us:

Just published

NHS England to redesign GP appraisal in light of COVID-19 pandemic

NHS England to redesign GP appraisal in light of COVID-19 pandemic

GP appraisals are being redesigned to have a greater focus on wellbeing and reduced...

Primary care to lose millions in funding unless PCNs hit recruitment targets in pandemic

Primary care to lose millions in funding unless PCNs hit recruitment targets in pandemic

Hundreds of millions of pounds could be lost to primary care if primary care networks...

Practices told to prepare for 'major expansion' of flu vaccination as QOF pared back for 2020/21

Practices told to prepare for 'major expansion' of flu vaccination as QOF pared back for 2020/21

GP practices have been told to 'gear up for a major expansion of the winter flu programme'...

NHS England unveils GP contract plans for second phase of COVID-19 response

NHS England unveils GP contract plans for second phase of COVID-19 response

GPs have been told to re-start health checks and other suspended services as NHS...

More than 80% of patients report 'good' overall experience of general practice

More than 80% of patients report 'good' overall experience of general practice

Public satisfaction with GP services remains high, with 82% of patients reporting...

GPs condemn 'deafening silence' from chancellor on COVID support funding

GPs condemn 'deafening silence' from chancellor on COVID support funding

GP leaders have condemned a 'deafening silence' on COVID-19 relief funding for general...