Ibuprofen benefits cystic fibrosis lungs

High-dose ibuprofen can slow the rate of lung decline in children with cystic fibrosis, according to a Cochrane review.

The updated review supports the theory that long-term high-dose treatment with the anti-inflammatory drug can slow down lung tissue deterioration.

Progressive lung damage contributes to the majority of cystic fibrosis deaths.

The latest review included four trials involving 287 patients aged five to 39 years, who were followed-up for a maximum of four years.

The studies provided some evidence that ibuprofen could slow lung decline. In one study, people treated with ibuprofen before the age of 13 had an annual 1.5 per cent drop in forced expiratory volume in 1 second (FEV1), compared with more than 4 per cent in those given placebo.

However, ibuprofen in cystic fibrosis is not currently recommended for routine use and patients should only be given the therapy in a specialist centre, warn the review authors.

rachel.liddle@haymarket.com

Comment below and tell us what you think

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Follow Us:

Just published

Javid must offer 'clear public backing for GPs', warns BMA

Javid must offer 'clear public backing for GPs', warns BMA

The BMA has demanded 'clear public backing' for general practice from the government...

How has COVID-19 impacted on continuity of care in general practice?

How has COVID-19 impacted on continuity of care in general practice?

Dr Jessica Farrell and Dr Kamal Sidhu look at clinicians’ views of how the pandemic...

‘Sick to the back teeth of press saying we're closed’ - GPs condemn media attacks

‘Sick to the back teeth of press saying we're closed’ - GPs condemn media attacks

After media campaigns criticising GPs on face-to-face access, doctors have spoken...

Podcast: GP access row, improving menopause care, COVID-19 boosters

Podcast: GP access row, improving menopause care, COVID-19 boosters

The team discusses the current media storm around face-to-face access, COVID booster...

Face-to-face GP appointments on demand 'unachievable', warns RCGP chair

Face-to-face GP appointments on demand 'unachievable', warns RCGP chair

Calls for general practice to offer face-to-face appointments to all patients who...

Cornwall PCN wheels out electric car fleet to reduce carbon footprint

Cornwall PCN wheels out electric car fleet to reduce carbon footprint

Staff at a primary care network (PCN) in Cornwall have committed to reducing their...