IBD patients face raised clot risk during flare-ups

Patients who have flare-ups of inflammatory bowel disease (IBD) and are not admitted to hospital are at high risk of venous thromboembolism, researchers have found.

The University of Nottingham researchers studied anonymised records of over 85,000 patients with and without IBD.

They found a 16-fold increase in risk of venous thromboembolism for patients with active IBD who are not hospitalised, compared with the general, ambulatory population.

Writing in The Lancet, they commented: ‘These results suggest that active IBD in ambulatory patients might be a far greater risk factor for venous thromboembolism than previously recognised.'

While thromboembolic prophylaxis is routinely given to patients admitted to hospital with inflammatory bowel disease, this study suggests that outpatients with active disease may also benefit from prophylaxis, the researchers said.

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