NHS England set out plans to raise the amount invested in general practice by £2.4bn a year by 2020 - which could take its share of total health service funding to around 10% - in the GP Forward View published earlier this year.
But GP leaders are challenging Theresa May's government to reaffirm its commitment to the GP funding increase following the resignation of former prime minister David Cameron in the wake of the EU referendum result.
More than 500 GPs and patients have taken action in support of the RCGP's push to secure the implementation of the GP Forward View over the past few days by writing to their local MPs, a college spokesman confirmed.
A statement on the RCGP website calling on the profession to support its initiative says that the fallout from the Brexit vote has created a 'time of real change for the country'.
It adds: 'Please help us ensure that one thing that doesn't change is the government's support for the GP Forward View.'
The college calls the Forward View a 'historic win for patients, addressing concerns about investment in the service and recruitment of GPs, as well as pledging an extra £2.4bn each year by 2020', and urges GPs to write to their MPs to put pressure on Theresa May to ensure it remains a 'top priority'.
A DH spokeswoman said: 'We want to make sure patients can get the right care at the right time from excellent, well-resourced GPs as part of our commitment to a seven-day NHS.
'That’s why we have backed NHS England’s GP Forward View with £2.4bn, which will be used to expand the GP workforce and buy in new technology to make consulting your GP as convenient as possible.'
The GP investment plans will be at the top of the agenda at this year's RCGP annual conference in Harrogate, but many GPs remain concerned that the Forward View does not go far enough to bring the crisis facing general practice to an end.