Healthy obesity a myth, study finds

Obesity raises the risk of MI and stroke even when traditional risk factors such as high BP or cholesterol are absent, according to a study that overturns the idea obesity can be 'benign' in some people.

Obesity: research scotches health myth
Obesity: research scotches health myth

Studies had suggested that some obese people may not face an increased risk of cardiovascular disease if their metabolic profile – including levels of blood sugar, cholesterol and other factors – is normal.

But a new meta-analysis has found that having a BMI of 30 for 10 years or more increases the risk of cardiovascular disease or death by a quarter – even among those who are metabolically ‘healthy’.

Authors of the study said clinicians and patients should not see obesity as a harmless condition. Doctors should consider both BMI and metabolic factors when assessing a person’s risk of cardiovascular disease, they said.

'No healthy obesity'

The international team of researchers examined data from eight studies into the effect of weight and metabolic profile on the risk of heart disease and death.

They analysed pooled data from 61,386 patients. There were 3,988 clinical events, including MI, acute coronary syndrome, heart failure, stroke and all-cause mortality.

Compared with metabolically healthy people of normal weight, people with a normal metabolic profile and a BMI over 30 faced a 24% increased relative risk of a cardiovascular event or death. This translates to a 0.7% greater absolute risk over 10-11 years.

In contrast, all metabolically unhealthy people had a similar risk of cardiovascular disease regardless of their BMI. This was more than double the risk of a metabolically healthy, normal-weight person.

Study authors said the concept of ‘benign obesity’ suggested by previous studies may only represent a short-term picture. Data suggests excess weight is linked to the initial development of unseen metabolic and vascular problems that lead to cardiovascular events in the longer term, they said.

The authors said: ‘Our results do not support this concept of "benign obesity" and demonstrate that there is no "healthy" pattern of obesity.’

They added: ‘Our findings highlight the need for comprehensive evaluation of not only BMI but also metabolic factors for the prediction of future morbidity and mortality.’

Particular attention should be given to normal-weight patients with an unhealthy metabolic profile, they advised.

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Follow Us:

Just published

GPs yet to receive thousands of pounds in QOF pay amid PCSE problems, says BMA

GPs yet to receive thousands of pounds in QOF pay amid PCSE problems, says BMA

Around 1,000 GP practices have yet to receive QOF payments potentially worth up to...

Vaccine gap leaves parts of England more exposed amid Delta variant surge

Vaccine gap leaves parts of England more exposed amid Delta variant surge

A far higher proportion of people have received both doses of COVID-19 vaccine in...

Bullying has continued in LMCs post-Romney review, GP whistleblower warns

Bullying has continued in LMCs post-Romney review, GP whistleblower warns

Bullying and sexism are continuing within local medical committees two years after...

UK COVID-19 vaccination programme tracker

UK COVID-19 vaccination programme tracker

GPs across the UK are playing a leading role in the largest-ever NHS vaccination...

No plans to impose face-to-face GP appointment targets, Hancock tells BMA

No plans to impose face-to-face GP appointment targets, Hancock tells BMA

The government has no plans to impose face-to-face appointments targets on general...

Coronavirus: Key guidance GPs need to know about COVID-19

Coronavirus: Key guidance GPs need to know about COVID-19

GPonline provides an overview of the key guidance relating to coronavirus, including...