NHS Greater Glasgow and Clyde plans to cut staffing levels by 1,252 over the next 18 months as part of a wider modernisation programme.
'By redesigning our services, including a move for some services onto fewer sites, we have identified that we can provide the same high-quality care for our patients with fewer staff,' a spokeswoman said.
A workforce report by the board warns that the closure of a hospital and cuts in trainee posts in the west of Scotland proposed by the Scottish government 'will result in a small decrease of approximately 21 whole time equivalent in the number of doctors in training in NHS Glasgow and Clyde'.
Dr Dean Marshall, chairman of GPC Scotland said the cuts were 'very worrying'.
'This will clearly have a knock-on effect on service delivery. Part of the plan would be to push more care into primary care, but without a shift in resources this will have an adverse impact on services.'