Genetic mutations are trigger for not result of melanoma

Genetic mutations could trigger the development of melanoma rather than being a result of the cancer, UK researchers say.

Scientists from the Institute of Cancer Research (ICR) previously found a mutated BRAF gene in 70% of people with melanoma, but it was unknown if the mutation was a cause or result of the cancer.

In a study funded by Cancer Research UK, the researchers found that the mutation leads to a cascade of genetic changes which causes the deadly melanoma.

Professor Richard Marais from the ICR said: ‘Understanding this process will help us develop more effective treatments for the disease.’

There are over 2,300 deaths in the UK from malignant melanoma each year.

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