Gastroenteritis vaccine success

Adding rotavirus to the childhood immunisation programme could prevent gastroenteritis episodes in the first two years of life, say Finnish researchers.

Each year in the EU, rotavirus is estimated to cause more than 200 deaths and nearly 700,000 out-patient appointments among the under-fives.

The study involved 3,994 children aged six to 14 weeks. Two-thirds were given two oral doses of human rotavirus vaccine. All were followed-up for an average of 17 months. Stool samples were collected in any bouts of gastroenteritis and tested for the presence of rotavirus.

Within six months of the first dose of vaccine being given, the researchers found an efficacy of 87.1 per cent in the treatment arm versus placebo. Two doses of rotavirus vaccine gave 78.9 per cent protection against rotavirus gastroenteritis of any severity.

Lancet 2007; 370: 1,757-63

Comment below and tell us what you think

 

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Follow Us:

Just published

Close up of hand holding sample tube with 'Omicron' handwritten on side

Government urged to 'free up' GP practices and expand steps to control Omicron

GPs have called for immediate action such as suspension of QOF to allow practices...

(Photo: Mike Kemp/Getty Images)

Coronavirus: Key guidance GPs need to know about COVID-19

GPonline provides an overview of the key guidance relating to coronavirus, including...

External wall of GP surgery with wording 'medical centre'

‘Utterly toxic’: GPs speak out over abuse and physical attacks on practice teams

GPs have condemned a rise in verbal and physical attacks on practice staff - warning...

Artist's image of a spiked virus

Javid warns of 'substantial risk' from new COVID-19 variant

The highly mutated COVID-19 variant B.1.1.529 'may pose a significant risk to public...

Desk with lettering 'LMC conference'

LMCs reject 'outdated' GMS contract and demand move to item of service payments

LMCs have voted to scrap the 'outdated and inadequate' GMS contract and to replace...

GPs at an LMC conference waving green voting cards in the air

LMCs demand ringfence on enhanced services cash and clear GP representation in ICSs

LMCs have called for a ringfence on enhanced services funding, along with a guarantee...