Firm stops trials of obesity drug

Sanofi-Aventis has discontinued all trials of its anti-obesity drug rimonabant (Acomplia), which was suspended by the European Medicines Agency last month.

At the time of the suspension, Sanofi-Aventis said it saw the suspension as temporary and that it hoped ongoing studies would provide additional evidence for the product's safety and benefit in patients with diabetes and cardiovascular disease.

The company has now announced that it has decided to discontinue the ongoing rimonabant clinical development programme in all indications.

The decision has been taken 'in light of recent demands by certain national health authorities', a spokesman said.

'As a result the feasibility of the global clinical development programme has been compromised.'

The EMEA withdrew the European Marketing Authorisation for Acomplia after an assessment of the drug's benefits and risks showed an increased risk of psychiatric disorders patients.

The agency said it believed that these side-effects could not be adequately addressed by risk minimisation measures.

tom.moberly@haymarket.com

Comment below and tell us what you think

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Follow Us:

Just published

NHS operating procedure for primary care to remain until UK lifts all COVID-19 restrictions

NHS operating procedure for primary care to remain until UK lifts all COVID-19 restrictions

The NHS standard operating procedure (SOP) for primary care will remain in place...

All adults in England to book COVID jab 'this week' as UK hits 30m second doses

All adults in England to book COVID jab 'this week' as UK hits 30m second doses

All adults should be able to book their first COVID-19 jab by the ‘end of this week’...

NHS faces workforce 'pinch point' as COVID-19 drives wave of retirements, warns GMC

NHS faces workforce 'pinch point' as COVID-19 drives wave of retirements, warns GMC

Numbers of doctors working in the NHS will soon reach a ‘pinch point’ unless immediate...

UK COVID-19 vaccination programme tracker

UK COVID-19 vaccination programme tracker

GPs across the UK are playing a leading role in the largest-ever NHS vaccination...

NHS England pledges £30m for GPs to boost long COVID diagnosis and care

NHS England pledges £30m for GPs to boost long COVID diagnosis and care

NHS England has promised £30m for general practice to improve diagnosis and care...

Second dose COVID jabs for over-40s to be accelerated as lifting restrictions is delayed

Second dose COVID jabs for over-40s to be accelerated as lifting restrictions is delayed

Second doses of COVID-19 vaccines in England will be 'accelerated' for all over-40s...