Evidence base: Postnatal depression

A summary of clinical trials, guidelines and online resources to help in the primary care management of postnatal depression.

Use of the term PND has reduced the stigma of the condition
Use of the term PND has reduced the stigma of the condition

Clinical trials

This paper looks at outcomes in PND patients based on training for health visitors to identify and deliver psychological interventions.

Chapter two (pages 13-16) details therapeutic evidence. Appendix two (page 167), an economic analysis of psychological interventions by health visitors, concludes that these approaches are cost-effective in terms of lower mean costs and higher mean QALYs gained in the intervention group.


Section 4 focuses on prescribing in pregnancy as well as lactation.

  • NICE. Antenatal and postnatal mental health. London, NICE, 2007.

  • The UK Teratology Information Service can be contacted on 0844 892 0909 (9am to 5pm Monday to Friday). This service is free for NHS clinicians.


By Dr Muffazal Rawala, specialist registrar in general adult psychiatry at South London and The Maudsley NHS Foundation Trust, London

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