Clinical trials
- The RTS,S Clinical Trials Partnership. N Engl J Med 2011; doi: 10.1056/NEJMoa1102287
This paper outlines early results of a continuing phase III study of the efficacy, safety and immunogenicity of candidate malaria vaccine RTS,S/AS01 in seven African countries. The results of the study so far have shown that the RTS,S/AS01 vaccine provided protection against both clinical and severe malaria in African children.
Guidelines
- Guidelines for malaria prevention in travellers from the United Kingdom were published by the Health Protection Agency in 2007.1
- Lalloo D, Shingadia D, Pasvol G et al have published helpful guidelines on the UK treatment of malaria.3
Key text
- Cox FEG. History of human parasitology. Clin Microbiol Rev 2002; 15(4): 595-612.
- Health Information for Overseas Travel 'Yellow Book'. National Travel Health Network and Centre, London, 2010. ISBN 978-095657920-1. Available at: www.nathnac.org/yellow_book/YBmainpage.htm Provides travel information for health professionals.
- National Travel Health Network and Centre. The Ill Returned Traveller: Diarrhoeal Illness. Available at www.nathnac.org/yellow_book/PostTravel-DiarrhoeaAlgorithm.pdf.pdf
Online
- The National Travel Health Network and Centre provides free pre-travel health advice at www.nathnac.org and offers a health professionals advice line service on 0845 602 6712.
- Health Protection Scotland. Fit for travel. Malaria. Available at: www.fitfortravel.nhs.uk/advice/malaria.aspx.
- Travax www.travax.org provides pre-travel information service for subscribing healthcare professionals.
- World Health Organisation: Malaria. Available at www.who.int/topics/malaria/en/
Contributed by Dr Adrian Rogers, a clinical assistant, and Dr Lisa Ford, a clinical lecturer, at the Well Travelled Clinic, Liverpool School of Tropical Medicine
