Evidence base: Malaria

A summary of the evidence base for the management of malaria

Bed nets and antimosquito body sprays should be used to prevent the spread of malaria (Photograph: SPL)
Bed nets and antimosquito body sprays should be used to prevent the spread of malaria (Photograph: SPL)

Clinical trials

This paper outlines early results of a continuing phase III study of the efficacy, safety and immunogenicity of candidate malaria vaccine RTS,S/AS01 in seven African countries. The results of the study so far have shown that the RTS,S/AS01 vaccine provided protection against both clinical and severe malaria in African children.


Key text


 Contributed by Dr Adrian Rogers, a clinical assistant, and Dr Lisa Ford, a clinical lecturer, at the Well Travelled Clinic, Liverpool School of Tropical Medicine


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