Clinical trials
- Tomlinson JW, Holden N, Hills RK, et al. Association between premature mortality and hypopituitarism. West Midlands Prospective Hypopituitary Study Group. Lancet 2001; 357: 425-31.
- Abs R, Feldt-Rasmussen U, Mattsson AF, et al. Determinants of cardiovascular risk in 2589 hypopituitary GH-deficient adults - a KIMS database analysis. Eur J Endocrinol 2006; 155: 79-90.
Guidelines
- The Endocrine Society. Evaluation and treatment of adult growth hormone deficiency: An endocrine society clinical practice fuideline. J Clin Endocrinol Metab 2006; 91: 1621-34.
- Ghigo E, Masel B, Aimaretti G, et al, Consensus guidelines on screening for hypopituitarism following traumatic brain injury. Brain Inj 2005; 19: 711-24. Consensus on screening and treatment of pituitary insufficiency following traumatic brain injury.
- Cook DM, Yuen KCJ, Biller BMK, et al. American Association of Clinical Endocrinologists medical guidelines for clinical practice for growth hormone use in growth hormone-deficient adults and transition patients - 2009 update. Endocr Pract 2009; 15 Suppl 2: 1-29. This is an updated version of the guideline which was published in 2003 by the American Association of Clinical Endocrinologists.
Key texts
- 'The pituitary' In: Turner H, Wass J. Oxford Handbook of Endocrinology and Diabetes. Oxford, Oxford University Press, 2009. This is a handy brief textbook reference.
- 'Neuroendocrinology and The Pituitary' In: De Groot LJ, Jameson JL. Endocrinology (5th Ed.). Philadelphia. Elsevier Health. 2005. This is a comprehensive textbook resource.
Online
- www.endotext.com - Chapter 12 of the Endocrine Resource - Hypopituitarism - is a definitive review of the subject.
- www.endobible.com/condition/hypopituitarism. This has a focus on clinical assessment.
- www.pituitary.org.uk Information on hypopituitarism and a section for GPs
Contributed by Dr Rajeev Raghavan, specialist registrar, and Dr Karin Bradley, consultant endocrinologist, University Hospitals Bristol NHS Foundation Trust
