Enzyme boost for diabetics

Administering the enzyme hyaluronidase with meal-time insulin injections could help improve blood sugar control in people with type-1 diabetes, US researchers believe.

Administering the enzyme hyaluronidase could assist blood sugar control
Administering the enzyme hyaluronidase could assist blood sugar control

Dr Marcus Hompesch and colleagues from the Profil Insitute for Clinical Research in California studied the enzyme, which accelerates the action of insulin analogues, in 22 people.

They found co-treatment with recombinant human hyaluronidase (rHuPH20) and insulin led to smaller rises in glucose levels after meals than treatment with insulin lispro alone.

'The results suggest that a coformulation of prandial insulins with rHuPH20 may benefit patients with diabetes by decreasing postprandial hyperglycaemic excursions without increasing the risk for late postprandial hypoglycaemic events,' they said.


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