Diastolic BP overtreatment raises CV risk

Pushing diastolic BP below 70mmHg in type-2 diabetes can increase the risk of cardiovascular events, US researchers have warned.

The team from Omaha’s Veterans’ Affairs Medical Center said that, although evidence supports upper BP treatment thresholds, there is little evidence on how far BP should be lowered.

The researchers studied 1,791 patients with type-2 diabetes and hypertension.

Their results supported treatment of patients with systolic BP about 140mmHg and a diastolic BP below 80mmHg.

But they also found that patients with a diastolic BP below 70mmHg were more than twice as likely as those with higher diastolic BP to suffer a cardiovascular event. This risk increased at even lower diastolic BPs - those with diastolic BPs below 60mmHg were 2.8 times more likely to suffer a cardiovascular event.

The researchers commented: ‘The results supported the conclusion that a diastolic BP of <70 mmHg is the level at which CVD risk begins to increase significantly, with further enhanced significant risks with diastolic BP <60 mmHg.’

They added: ‘A possible negative effect of antihypertensive treatments that excessively lower DBP must be considered.’

The researchers said that future studies should look at whether BP control changed outcomes for individual patients in higher risk systolic of diastolic BP categories.

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Follow Us:

Just published

UK COVID-19 vaccination programme tracker

UK COVID-19 vaccination programme tracker

GPs across the UK are playing a leading role in the largest-ever NHS vaccination...

GP-led sites behind almost three quarters of COVID-19 jabs in England

GP-led sites behind almost three quarters of COVID-19 jabs in England

GP-led vaccination sites have delivered nearly three quarters of COVID-19 vaccine...

GPs should ignore calls to throw away usable COVID-19 vaccine, says RCGP

GPs should ignore calls to throw away usable COVID-19 vaccine, says RCGP

Suggestions that vaccination sites should throw away usable doses of COVID-19 vaccine...

GPs urged to use influence to dispel COVID-19 vaccine myths and boost BAME uptake

GPs urged to use influence to dispel COVID-19 vaccine myths and boost BAME uptake

GPs have been encouraged to use their ‘huge influence’ to bust misinformation around...

Six in 10 over-80s vaccinated against COVID-19 as figures expose regional variation

Six in 10 over-80s vaccinated against COVID-19 as figures expose regional variation

Six in 10 people aged over 80 in England received a first dose of COVID-19 vaccine...

Summary of changes to the GP contract 2021/22

Summary of changes to the GP contract 2021/22

The BMA and NHS England have agreed minor changes to the GP contract for 2021/22....