Diabetes drug can cut obesity in non-diabetics

The diabetes drug liraglutide could be used to treat obesity in non-diabetics and could also cut the risk of prediabetes, Danish research suggests.

The latest findings come as Diabetes UK warns that seven million people in the UK could be suffering from prediabetes.

The charity has developed a position statement calling for guidance to help diagnose and manage prediabetes.

The Danish study involved 564 patients, aged 18 to 65, with a BMI of 30 to 40. They received 1.2mg, 1.8mg, 2.4mg or 3.0mg of liraglutide or placebo once daily, or 120mg of orlistat three times a day orally.

All patients were asked to follow a calorie-restricted diet during the 20-week study, and to increase physical activity.

Levels of weight loss increased the higher the dose of liraglutide, with the 3.0mg dose causing a mean weight loss of 7.2kg. This compared with a weight loss of 4.1kg with orlistat and 2.8kg with placebo.

Prevalence of prediabetes also fell between 84 and 96 per cent with liraglutide treatment.

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Follow Us:

Just published

Wide-ranging overhaul of GP bureaucracy promised amid spiralling practice workload

Wide-ranging overhaul of GP bureaucracy promised amid spiralling practice workload

Revalidation, referral processes, coding of patient data and letters required from...

Recognising and referring domestic violence and abuse

Recognising and referring domestic violence and abuse

A social enterprise is helping to train staff in GP practices to support women affected...

GPs 'in the dark' over pension tax trap support for this year

GPs 'in the dark' over pension tax trap support for this year

GPs remain in the dark over how a stop-gap offer from NHS England to pay off pension...

Network DES will cost GPs money and threaten independent contractor status, warn LMCs

Network DES will cost GPs money and threaten independent contractor status, warn LMCs

A group of LMCs has warned it 'cannot recommend' GPs sign up to revised plans for...

'A Hard Day's Night': a GP's musical reaction to the updated contract

'A Hard Day's Night': a GP's musical reaction to the updated contract

The life of a GP can be incredibly busy, but that hasn't stopped one talented doctor...

Viewpoint: Revamped 2020 contract 'a watershed moment for general practice'

Viewpoint: Revamped 2020 contract 'a watershed moment for general practice'

Following weeks of uncertainty over the future of primary care networks (PCNs), reworked...