Depression and type-2 diabetes are each independently associated with increased mortality in CAD patients.
But CAD patients with type-2 diabetes and depression have a 20-30 per cent increased risk of dying compared to those without type-2 diabetes, the researchers told the annual meeting of the American Psychosomatic Society in Budapest.
The study included 907 CAD patients, 325 with type-2 diabetes who were assessed for depression.
Mortality risk was associated with the level of depression in CAD patients with type-2 diabetes.
Lead researcher Dr Anastasia Georgiades from Duke University in Durham, North Carolina said: 'Our data shows an interaction between type-2 diabetes and depression, so physicians should monitor their heart patients who have both disorders.'