Cot death link to brain abnormalities

A study in the Journal of the American Medical Association has shown that cellular defects in the brainstem may be a risk factor for sudden infant death syndrome (SIDS).

Sleeping baby
Sleeping baby
These abnormalities mean that a baby is unable to process serotonin (5-HT) a neurotransmitter essential for homeostatic control.

Serotonergic (5-HT) neurons project extensively in to the brainstem which helps regulate homeostatic functions such as breathing and temperature control.

Previously, abnormalities in 5-HT receptor binding had been identified in infants dying from SIDS. The authors of this study, therefore, investigated cellular defects in the 5-HT pathways of the medulla in SIDS cases.

The study revealed that the brainstems of SIDS cases had more serotonergic neurons, but less 5-HT receptors.

It is hoped that the results will provide some further evidence towards understanding SIDS.

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Follow Us:

Just published

Five GP practices a week inspected by CQC during pandemic second wave

Five GP practices a week inspected by CQC during pandemic second wave

The CQC has inspected five GP practices a week in England since the second wave of...

Pregnant women and under-18s will not be offered COVID-19 vaccine

Pregnant women and under-18s will not be offered COVID-19 vaccine

Pregnant women, children and under-18s will not be recommended for routine COVID-19...

GP training: How an audit e-portfolio log entry is assessed

GP training: How an audit e-portfolio log entry is assessed

The second of two articles on audit during GP training looks at how the quality improvement...

GP training: Writing up an audit for your e-portfolio

GP training: Writing up an audit for your e-portfolio

In the first of two articles on how to write up an audit, a typical e-portfolio entry...

UK ups order of 95% effective COVID-19 vaccine by 2m doses

UK ups order of 95% effective COVID-19 vaccine by 2m doses

The UK has increased its order of the 95% effective Moderna COVID-19 vaccine to 7m...

Coronavirus: Key guidance GPs need to know about COVID-19

Coronavirus: Key guidance GPs need to know about COVID-19

GPonline provides an overview of the key guidance relating to coronavirus, including...