Cardiovascular 'polypill' trial launched in UK

Human trials of a cardiovascular polypill are being launched in the UK this week.

Patients at increased risk of heart attack or stroke will be given one year’s treatment with a pill containing low doses of aspirin, a statin, an ACE inhibitor and a thiazide diruetic, or a placebo.

The researchers will then examine whether the pill is able to reduce patients’ risk of cardiovascular events. Patients from six countries, including the UK, are being enrolled in the study.

The 700-patient trial is being led by Professor Simon Thom and Professor Neil Poulter of the International Centre for Circulatory Health at Imperial College, London.

If this pilot study is a success, a larger study involving up to 7,000 patients will be launched at the end of 2009.

The Indian generics company Dr Reddy’s is manufacturing the pill, which it has named the Red Heart pill.

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