BP drug could protect against Parkinson's

Calcium channel blockers may be able to reduce the risk of Parkinson’s disease by almost a quarter, Swiss research suggests.

But other BP medications such as ACE inhibitors and beta-blockers have no effect on the development of the disease.

For the study, the researchers performed a retrospective analysis using data on 7,374 patients, over the age of 40, taken from the UK general practice research database. 

A total of 3,637 cases of Parkinson's were recorded between 1994 and 2005. A control group of 3,637 healthy patients without Parkinson's were then matched to the Parkinson's group.

Among both groups, 3,000 patients were using antihypertensive drugs. Of these, 948 were using calcium channel blockers.

Analysis showed that patients taking calcium channel blockers were 23 per cent less likely to develop Parkinson's than those who did not take BP drugs.

But no protective effect was found for ACE inhibitors, angiotensin II antagonists or beta-blockers.

sanjay.tanday@haymarket.com

Neurology Journal

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