In a close vote at the BMA annual representative meeting in Bournemouth, 158 representatives backed a motion calling for Mr Lansley to quit, with 124 voting against.
The vote was carried despite outgoing BMA chairman Dr Hamish Meldrum warning it was difficult to negotiate with someone ‘after you have handed them their P45’.
GPC negotiator Dr Peter Holden told the conference that he was a card-carrying Tory and believed ‘resignation is too good for Lansley, Cameron should sack him’.
The motion put forward by the City and Hackney division said: ‘That this meeting has no confidence in Andrew Lansley, the Secretary of State for Health, and calls for him to resign’
The conference also overwhelmingly backed motions calling for further industrial action on pensions. They backed motions stating that further action should include withdrawal from clinical commissioning, despite a vote earlier in the week against this.