Beta-blockers cut CVD mortality risk in COPD

Beta-blockers can cut the risk of death from CVD by 40 per cent in patients with COPD without hindering lung function, US research suggests.

CVD is the leading cause of death in patients with COPD, with coronary artery disease present in 10-22 per cent of COPD patients.

But the use of beta-blockers is not always advocated in COPD patients because of concerns about possible adverse effects of beta-blockade on airway function.

NICE guidance on COPD management, issued in February 2004, does not make any recommendations for beta-blocker use.

For this latest study , the researchers identified 825 patients, of which 142 were on beta-blockers, admitted between October 1999 and September 2006 to hospital with acute exacerbations of COPD. Patients with a diagnosis of asthma were excluded from the study. Over the duration of the seven-year study, 43 patients died from CVD.

When the mortality rate was compared for those who received beta-blockers and those who did not, they found that beta-blocker use could reduce CVD mortality by 40 per cent compared to no beta-blocker use.

While in a subset of patients with available spirometric data, no significant difference was found between those who received beta-blockers and those who did not in percent predicted FEV1.

sanjay.tanday@haymarket.com

Comment below and tell us what you think

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Follow Us:

Just published

More than half of GP locums have seen a significant drop in income due to COVID-19

More than half of GP locums have seen a significant drop in income due to COVID-19

More than half of GP locums have experienced a significant fall in their income during...

How a GP helped develop a protective shield to cover patients needing CPR in the pandemic

How a GP helped develop a protective shield to cover patients needing CPR in the pandemic

Wiltshire GP Dr Lydia Campbell-Hill explains how she helped create a mini isolation...

GP practices can now sign up to new online PPE portal

GP practices can now sign up to new online PPE portal

GP practices will be able to register with the DHSC's new online PPE portal, which...

Fully-qualified GP workforce fell by 712 over the past year

Fully-qualified GP workforce fell by 712 over the past year

The fully-qualified GP workforce in England fell by 2.5%, losing 712 full-time equivalent...

MPs call for expert guidance on medico-legal implications of pandemic

MPs call for expert guidance on medico-legal implications of pandemic

A group of MPs has called on the government to set up an independent expert committee...

Coronavirus: Key guidance GPs need to know about COVID-19

Coronavirus: Key guidance GPs need to know about COVID-19

GPonline provides an overview of the key guidance relating to coronavirus, including...