Beta-blockers cut CVD mortality risk in COPD

Beta-blockers can cut the risk of death from CVD by 40 per cent in patients with COPD without hindering lung function, US research suggests.

CVD is the leading cause of death in patients with COPD, with coronary artery disease present in 10-22 per cent of COPD patients.

But the use of beta-blockers is not always advocated in COPD patients because of concerns about possible adverse effects of beta-blockade on airway function.

NICE guidance on COPD management, issued in February 2004, does not make any recommendations for beta-blocker use.

For this latest study , the researchers identified 825 patients, of which 142 were on beta-blockers, admitted between October 1999 and September 2006 to hospital with acute exacerbations of COPD. Patients with a diagnosis of asthma were excluded from the study. Over the duration of the seven-year study, 43 patients died from CVD.

When the mortality rate was compared for those who received beta-blockers and those who did not, they found that beta-blocker use could reduce CVD mortality by 40 per cent compared to no beta-blocker use.

While in a subset of patients with available spirometric data, no significant difference was found between those who received beta-blockers and those who did not in percent predicted FEV1.

Comment below and tell us what you think

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins


Already registered?

Sign in

Follow Us:

Just published

Renewable energy

GP practices can be 'more ambitious' on tackling climate change

GP practices can be more ambitious in taking steps to tackle climate change than...

GP surgery sign

Risks of being a partner have outstripped benefits, GPs told

The risks of being a partner have become greater that the benefits, the RCGP conference...

Image of Dr Farzana Hussain

GPs urged to use their voices to improve the lives of patients in deprived areas

The can-do attitude and independence of GPs offers a unique opportunity to help reverse...

Professor Sir Michael Marmot

Unequal impact of COVID-19 'utterly predictable' amid rising inequality, says Marmot

The disproportionate impact of COVID-19 on people in the most deprived parts of England...

Consulting room door

NHS on course for shortfall of 11,000 GPs within a decade

One in four GP and practice nurse posts will be vacant within a decade without a...

Dr Iona Heath

Lessons from the COVID-19 pandemic can help GPs tackle health inequalities

GPs can use evidence from the COVID-19 pandemic to put pressure on the government...