Avandia should be suspended, says European regulator

The diabetes drug Avandia (rosiglitazone) should be suspended from use in Europe, according to the European Medicines Agency (EMA).

The EMA recommended drugs Avandia, Avandamet and Avaglim should be suspended from sale in Europe. It follows a review of the evidence for safety of the drugs by the EMA’s Committee for Medicinal Products for Human Use (CHMP).

MHRA chief executive Professor Kent Woods said: 'Today’s suspension means that clinicians should review all patients currently on rosiglitazone and take appropriate action, according to the individual clinical situation, to change to another suitable treatment.’

The CHMP said data have suggested a possible increased risk of ischaemic heart disease associated with the use of rosiglitazone.

The committee concluded that ‘the benefits of rosiglitazone no longer outweigh its risks and recommended the suspension of the marketing authorisation of the medicines’.

As such, it will no longer be available in Europe within the next few months, unless further data showing benefit can be presented by the manufacturer.

Patients who are currently taking these medicines should make an appointment with their doctor to discuss suitable alternative treatments, the EMA said.

Patients are advised not to stop their treatment without speaking to their doctor.

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register

Already registered?

Sign in

Follow Us:

Just published

First MDO completes switch to state-backed GP indemnity across England and Wales

First MDO completes switch to state-backed GP indemnity across England and Wales

The Medical Protection Society (MPS) has become the first of the three main providers...

GPs face unsustainable pressure, warns GMC report on doctors' wellbeing

GPs face unsustainable pressure, warns GMC report on doctors' wellbeing

GPs are working under intense and unsustainable pressure that has eroded their relationship...

'Unrealistic' wage bands could mean PCNs lose funding for new staff

'Unrealistic' wage bands could mean PCNs lose funding for new staff

Salary bands for clinical pharmacists working in primary care networks (PCNs) are...

GP at Hand now has third largest patient list in England

GP at Hand now has third largest patient list in England

Controversial digital-first provider GP at Hand now has the third largest registered...

Viewpoint: 'Why the RCGP should change its stance on assisted dying'

Viewpoint: 'Why the RCGP should change its stance on assisted dying'

The RCGP is currently surveying members for their views on assisted dying. Dr Zoe...

RCGP urges caution over call to scrap home visits

RCGP urges caution over call to scrap home visits

Workload pressures are forcing GP practices into tough decisions about which services...