Aspirin boost to colon cancer test

Low-dose aspirin may improve the performance of tests for colorectal cancer, a study suggests.

German researchers looked at the issue because screening for colorectal cancer is often carried out in populations in whom use of low-dose aspirin is common.

Low-dose aspirin increases the risk of gastrointestinal bleeding and so concerns have been raised that it may affect the specificity of tests for colorectal cancer.

Dr Hermann Brenner and colleagues from the German Cancer Research Centre in Heidelberg assessed the performance of immunochemical faecal occult blood tests in around 4,000 people.

They found that the use of low-dose aspirin was associated with a markedly higher sensitivity for detecting advanced colorectal neoplasms, with only a slightly lower specificity.

The researchers said the possibility that test performance may be enhanced by temporary use of low-dose aspirin will need to be followed up in large randomised studies.

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins


Already registered?

Sign in

Follow Us:

Just published

NHS sign

Plans to recruit 1,000 new link workers to support GP practices this winter

NHS England has set out plans to recruit an additional 1,000 social prescribing link...

BMA House

BMA prepares to ballot junior doctors on industrial action

Junior doctors will be balloted over industrial action if the government does not...

Typing on a laptop

NHS 111 systems could be offline until next week following cyber attack

NHS 111 systems could be offline until next week following the cyber attack on a...

The NHS App in the Apple App store on a smart phone

NHS England piloting online patient registration for GP practices

A new system that will allow patients to register with a GP surgery online is being...

satisfaction scale

Which parts of England have the highest and lowest GP patient satisfaction?

Patient satisfaction with GP services varies widely between PCN and ICS areas across...

Talking General Practice logo

Podcast: Improving menopause care

During August we’re bringing you some of the best interviews from series one of the...